Today's New York Times reports that in light of recent trials of Zetia and Vytorin, maybe lowering cholesterol isn't the way to prevent heart disease. This is huge. And it's about #$!%ing time!
As I mentioned in a previous post, these trials shouldn't have come as a surprise to anyone who has reviewed the research and trial data on heart disease. For my master's thesis on genomics at Columbia, I found out very quickly that cholesterol isn't the cause of heart disease. If anything, it's what's known as a "risk factor." That is, for some people, high cholesterol could mean that they're more likely to develop heart disease. But even on that count, it's a highly unreliable measure. Or, to put it more bluntly, the whole cholesterol theory which has dominated cardiology for the past four decades, is a house of cards. And who am I? A scientist? A cardiologist? Hardly! I'm a journalist, for God's sake. How hard can this be to figure out?
Could the world finally be waking up to this? If so, the implications are massive. No more low-fat diets. No more enforced statin therapy for anyone with cholesterol over 160. And maybe, just maybe, the way will be cleared for a new set of theories, so that the western world's number one killer can finally be stopped. And to that, I say hallelujah.
Thursday, January 17, 2008
Could the cholesterol house of cards be falling?
Posted by Sunshine at 9:57 AM
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